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“That exacerbation took a lot out of me, and I didn’t recover.” That’s when his doctor first brought up the idea of a lung transplant. that does lung transplants on cystic fibrosis patients who test positive for B. For Perron, this was like a light at the end of the tunnel.However, because of an aggressive type of bacteria Perron has in his lungs — known more commonly as B. “Having a hospital system like UPMC brought me a lot of comfort,” Perron said.In people with two copies of the mutation, the clinical features of cystic fibrosis develop.
, a genetic disease that causes thick mucus to form in the lungs.
The CFTR protein maintains a balance of fluid and salt in the cell.
When a mutation occurs in the gene, CFTR functions poorly, and salt is not transported properly.
Cystic fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
The protein coded by CFTR is an ion channel--a protein that regulates the passage of salt into and out of a cell.
Cystic fibrosis is a disease known for causing lung disease and serious illness beginning from babyhood or early childhood.